Acetylcysteine for Acetaminophen Poisoning

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منابع مشابه

Acetylcysteine for acetaminophen poisoning.

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author’s clinical r...

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N-Acetylcysteine Overdose After Acetaminophen Poisoning

N-acetylcysteine (NAC) is a drug  used  widely and effectively in oral  and  ‎intravenous  forms  as  a  specific  antidote  for acetaminophen poisoning.  In children ‎considering the toxic dose of acetaminophen ingested by the patient and the body weight, the ‎physician prescribes a specific dose of NAC. There is always a risk of  iatrogenic overdose of  ‎NAC  which can cause different mild to...

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N-Acetylcysteine Overdose After Acetaminophen Poisoning

N-acetylcysteine (NAC) is a drug  used  widely and effectively in oral  and  ‎intravenous  forms  as  a  specific  antidote  for acetaminophen poisoning.  In children ‎considering the toxic dose of acetaminophen ingested by the patient and the body weight, the ‎physician prescribes a specific dose of NAC. There is always a risk of  iatrogenic overdose of  ‎NAC  which can cause different mild to...

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N-acetylcysteine overdose after acetaminophen poisoning

N-acetylcysteine (NAC) is used widely and effectively in oral and intravenous forms as a specific antidote for acetaminophen poisoning. Here we report a rare case of iatrogenic NAC overdose following an error in preparation of the solution, and describe its clinical symptoms. Laboratory results and are presented and examined. A 23-year-old alert female patient weighing 65 kg presented to the em...

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Oral or intravenous N-acetylcysteine for acetaminophen poisoning?

Acetaminophen (paracetamol, N-acetyl-p-aminophenol) is an effective, mild analgesic, antipyretic agent and is probably the most widely used of all drugs in the world. It does not share the formidable prostaglandin-dependent toxicity of aspirin and other conventional nonsteroidal anti-inflammatory agents, and when used properly, it has an excellent safety record. In many countries, it is fashion...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2008

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmct0708278